Therefore, there is an urgent need for innovative in vitro assays which allow researchers to evaluate their drug candidates in conditions mimicking better the human biology. This allows to make “go / no go” strategic decisions based on relevant efficacy and safety data packages at early stages, with a real impact on development in terms of startegy, costs and time to market. And at the end, more and safer new medicines for patients.
SecretCells® is a microfluidic lab-on-a-chip allowing efficay and cytotoxicity assays which combines perfused 3D cell culture capacities (to better mimic in-vivo like conditions) with the simultaneous capture of up to 10 secreted biomarkers on a removable biosensor.
SecretCells® is easy to implement, just requiring daily used equipments (incubators, peristaltic or syringe pumps, fluorescence microscope or slide scanner) and does not need fastidious training of lab staff. Biomarkers evaluation is performed through a microarray, based on a sandwich ELISA method.
SecretCells® is the most flexible system for perfusion cell culture with both 3D and 2D cell culture capacities.
SecretCells® biosensors and reagents kits are customizable to fit your biomarkers requirements.
Nanobiose proposes ready to use kits for the evaluation of different of biomarker panels and accessories to simplify daily labworks.
SecretCells combine microfluidics, removable biosensors and perfused 3D/2D cell culture technologies.