In vitro efficacy assays based on secreted biomarkers

SecretCells is formed by the reversible assembly of a biochip to a glass based biosensor. Cells are grown in either 2D or 3D, depending on the experimental setup, under a controlled perfusion of nutrients and compounds to be tested. Specific protein probes are grafted on the biosensor surface to create a microarray for the capture of secreted biomarkers. Biomarkers secretion is evaluated after incubation with specific reagents (ELISA sandwich) by imaging the biosensor surface for fluorescent signals.

nanobiose lab on a chip based assays

Microfluidics

Microfluidic systems offer many advantages:

Biosensors

Nanobiose develops biosensors dedicated to multiplexed analysis of secreted biomarkers.

nanobiose biosensors
nanobiose nanodrug candidates

Real-time capture of secreted biomarkers

Real-time provides access to critical information to understand biological processes, without multiplying the number of samples or assays.

Real-time capture of biomarkers on the biosensor allows to :

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