Therefore, there is an urgent need for innovative in vitro assays which allow researchers to evaluate their drug candidates in conditions mimicking better the human biology. This allows to make “go / no go” strategic decisions based on relevant efficacy and safety data packages at early stages, with a real impact on development in terms of strategy, costs and time to market. And at the end, more and safer new medicines for patients.
SecretCells® is a microfluidic lab-on-a-chip allowing efficay and cytotoxicity assays. It combines perfused 3D cell culture capacities (to better mimic in-vivo like conditions) with the simultaneous capture and detection of up to 10 secreted biomarkers on a removable biosensor.
Control the exposure of your cells, parallelize SecretCells® units to study dose related effects or combine to connect different cells types together: SecretCells® offers an almost infinite landscape of possibilities.
And to perfectly fit with your requirements, biosensors and reagents kits are customizable.
SecretCells® is easy to implement, just requiring daily used equipments (incubators, peristaltic or syringe pumps, fluorescence microscope or slide scanner) and does not need fastidious training of lab staff. Biomarkers evaluation is performed through a microarray, based on a sandwich ELISA method.
Nanobiose proposes ready to use kits for the evaluation of different of biomarker panels and accessories to simplify daily labworks.
SecretCells combine microfluidics, removable biosensors and perfused 3D/2D cell culture technologies.